When having Charon switch from melee combat to ranged weapons, he will make a remark which alludes to the song called ' Happiness Is a Warm Gun' by The Beatles. This is an allusion to the line ' I love the smell of napalm in the morning.' spoken by the character Lieutenant Colonel William 'Bill' Kilgore in the movie Apocalypse Now. The Mister Gutsy model of robot often says, ' There is nothing I like better than the smell of plasma in the morning.' when in combat.
The Vault-Tec Corporation Eye-On-You camera resembles the camera eye for HAL 9000 of the Discovery One from Stanley Kubrick's 1968 movie 2001: A Space Odyssey. In 1984, persons accused of 'thought crime' are taken to a place called Room 101 and tortured until they comply (or are simply executed). There are three references to the book Nineteen Eighty-Four: A Novel by George Orwell.